Eleven : Eleven Input Calibration and QuickStart : Connect your Guitar and Configure Source Input

Connect your Guitar and Configure Source Input
If your setup includes pedals or other gear, it helps to know whether the final output device is providing an instrument- or line-level signal. Choose and configure your input and source settings accordingly. (Check the Setup Guide that came with your system for more information.)
To connect your guitar to a Pro Tools host-based system:
1 Do one of the following, depending on your hardware configuration:
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If you are using an interface that has a DI input (such as an Mbox Pro), plug your guitar into an available DI input.
– or – 
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If you are using your computer’s built-in inputs, plug your guitar into an available input.
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If you use a direct box to convert your guitar’s hi-impedance output to a low-impedance signal, connect the direct box to a mic or line input instead of the DI input.
2 Make sure to use the correct input on your interface. For example, on Mbox Pro, plug your guitar into front-panel DI Inputs 1 or 2.
 
To connect your guitar to a Pro Tools|HD system:
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Mbox Pro back-panel 1/4” inputs are line-level only and should not be used with a guitar.
1 Make sure you have a pre-amp (such as an Avid PRE®) or similar unit connected to a Pro Tools|HD audio interface. (Note that HD OMNI provides built-in preamps.)
2 Plug your guitar into an available pre-amp input and set its source, impedance, and other settings as needed for your setup.
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If you use a direct box to convert your guitar’s hi-impedance output to a low-impedance signal, set the Line/Inst 1 input to Line source or the equivalent on your particular pre-amp.
For example, if using a Avid PRE you can plug your guitar directly into the front panel Line/Inst 1 input, then set its source to Inst.